How prebiotics have been produced from agro-industrial waste: An overview of the enzymatic technologies applied and the models used to validate their health claims

The disposal of waste from the food industry represents a major environmental concern. Nonetheless, agro-industrial by-products can be enzymatically converted into low-cost high-value-added products, such as prebiotics, while contributing to circular economy. As first approach for health claims validation these novel several gastrointestinal models have been used. main objective this review is provide comprehensive overview advances in enzymatic technologies applied production prebiotics wastes. strategies used conversion wastes, including pre-treatment processes, type enzymes applied, and reaction conditions are revised. Finally, data obtained by vivo trials vitro simulation, functionality produced their biological mechanisms action discussed. Enzymatic processes proven efficiency wastes commercial valuable compounds, prebiotics. Still, potential bioconversion vast diversity existing has yet explored. By researching different setups optimization conditions, greater yields prebiotic extraction or synthesis may achieved. Also, despite many available models, few studies done on function which drawback associated with products.